Food Preservative Natamycin Powder - Natural Antifungal Agent for Food Preservation
Introduction to Natamycin Technology
Natamycin stands as the most effective natural antifungal preservative approved for food applications worldwide. Our high-purity Natamycin Powder is derived through controlled fermentation of Streptomyces natalensis, offering food manufacturers a powerful yet clean-label solution against mold and yeast contamination. This polyene macrolide compound has become indispensable in the food industry, particularly for surface treatment applications where targeted fungal protection is required without compromising product quality or safety.
Product Specifications & Key Characteristics
Source: Produced by fermentation of Streptomyces natalensis
Purity: ≥95% natamycin content
Form: White to cream-colored crystalline powder
Solubility: Slightly soluble in water (30-100mg/L at 20°C), better in acidic solutions
pH Stability: Most effective between pH 3-9
Thermal Stability: Maintains activity at pasteurization temperatures
Certifications: Complies with FAO/WHO JECFA, FCC, EU (E235) standards
Mechanism of Action & Microbial Spectrum
Natamycin exhibits a unique fungistatic action through:
Membrane Binding: Specifically binds to ergosterol in fungal cell membranes
Cell Disruption: Creates pores that cause leakage of cellular contents
Growth Inhibition: Prevents spore germination and mycelial growth
Effective Against:
Surface molds (Aspergillus, Penicillium, Fusarium)
Yeasts (Saccharomyces, Candida, Zygosaccharomyces)
Mycotoxin-producing fungi
Food spoilage fungi resistant to other preservatives
Primary Food Applications
Dairy Product Protection:
Cheese Surface Treatment: Prevents mold growth on hard/semi-hard cheeses (0.5-2mg/dm²)
Yogurt & Fermented Dairy: Controls surface contamination
Butter & Margarine: Extends shelf life (5-10ppm)
Dairy Powder: Prevents caking from moisture absorption
Meat & Cured Product Applications:
Dry-Cured Meats: Surface treatment for sausages and hams (1mg/cm²)
Fermented Meats: Protection during aging process
Poultry Products: Extends refrigerated shelf life
Bakery & Confectionery:
Baked Goods: Surface spray for cakes and breads (5-15ppm)
Pastry Fillings: Prevents yeast spoilage
Chocolate Products: Controls sugar bloom fungi
Other Specialty Applications:
Fruit Preservation: Post-harvest treatment for tropical fruits
Beverage: Fermentation control in some alcoholic drinks
Food Packaging: Incorporated into active packaging materials
Technical Advantages for Food Manufacturers
1. Natural Preservation Benefits:
Clean-label alternative to chemical fungicides
GRAS status in multiple jurisdictions
No impact on product taste or aroma at recommended levels
2. Targeted Action Profile:
Surface-active with minimal penetration
Does not affect bacterial fermentation processes
Maintains product texture and quality
3. Processing Stability:
Heat-resistant up to 100°C for short periods
Stable in high-salt environments
Retains activity during refrigeration and freezing
4. Regulatory & Consumer Advantages:
Approved for organic production in many regions
No resistance development in target organisms
Meets clean-label consumer demands
Regulatory Status & Safety Profile
Global Approvals:
FDA: 21CFR172.155 (≤20ppm in specified foods)
EU: Approved as E235
China: GB 1886.103-2015
JECFA ADI: 0-0.3 mg/kg body weight
Safety Characteristics:
Non-toxic to humans at food-use levels
Minimal absorption in digestive tract
Over 40 years of safe commercial use
Naturally degraded in the environment
Quality Assurance & Production Standards
Our natamycin production follows:
cGMP-compliant fermentation processes
Stringent purification protocols
Potency verification through HPLC
Complete traceability documentation
Typical Certificate of Analysis Includes:
Natamycin content (%)
Water activity
Heavy metal limits
Microbial purity
Residual solvent testing
Usage Guidelines & Best Practices
Application Methods:
Dipping: 500-2000ppm suspension
Spraying: 1000-4000ppm solution
Dusting: Powder blends for surface application
Incorporation: Direct addition to some formulations
Optimal Application Parameters:
pH Range: Effective between pH 3-9
Temperature: Apply below 50°C for solution stability
Coverage: Ensure complete surface application
Combination: Often used with sorbates for enhanced spectrum
Recommended Dosage Ranges:
Cheese surface treatment: 0.5-2mg/dm²
Meat products: 1-5ppm
Baked goods: 5-15ppm
Beverages: 2-10ppm
Why Choose Our Natamycin Powder?
1. Product Superiority:
Higher purity than standard preparations
Optimized particle size for dissolution
Consistent biological activity
2. Technical Support:
Application-specific method development
Dosage optimization assistance
Regulatory documentation support
3. Supply Chain Advantages:
Temperature-controlled storage
Flexible packaging options
Global regulatory compliance
Market-Specific Benefits
For Dairy Processors:
Natural mold prevention for artisanal cheeses
Extends export product stability
Reduces surface trimming losses
For Meat Producers:
Clean-label alternative to traditional fungicides
Maintains product appearance during aging
Complies with organic processing requirements
For Bakery Manufacturers:
Prevents visible mold growth
Extends fresh presentation period
No impact on dough fermentation
Environmental Profile:
Biodegradable compound
Non-persistent in environment
Sustainable fermentation production
PSA | 231 |
XLogP3 | 1.1 |
Appearance | aqueous suspension |
Density | 1.4±0.1 g/cm3 |
Melting Point | 290 °C (decomp) |
Boiling Point | 952 |
Flash Point | >110°(230°F) |
Refractive Index | 1.62 |
Water Solubility | soluble in DMSO |
Storage Conditions | 2-8°C |
Toxicity | LD50 orally in male, female rats (g/kg): 2.73, 4.67 (Levinskas) |
Specific rotation | D20 +278° (c = 1 in CH3COOH) |
PH | 5,5-7,5 (1 % w/v solution in previously neutralised mixture of 20 parts dimethylformamide and 80 parts of water) |


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